What are mutational patterns, and do they affect outcomes of patients with acute myeloid leukemia?

During the EHA 2022 Congress, Know AML spoke with Brian Huntly, University of Cambridge, Cambridge, UK. We asked, What are mutational patterns, and do they affect outcomes of patients with acute myeloid leukemia (AML)?

Huntly begins by describing how combinations of mutations can lead to leukemia, and the developments we have seen in cytogenetics. Huntly outlines how mutational panels can be used in a prognostic setting, as well as current investigations into novel therapies.